14-3-3E; 143E; KCIP-1; Mitochondrial import stimulation factor L subunit; Protein kinase C inhibitor protein-1
Antigen
YWHAE
Categories
Primary Antibodies
Clonality
polyclonal
Description
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.Conklin D.S., Proc. Natl. Acad. Sci. U.S.A. 92:7892-7896(1995).Jin D.-Y., Nature 382:308-308(1996).Chong S.S., ome Res. 6:735-741(1996).
Host
Rabbit
Immunogen
Synthesized peptide derived from C-terminal of Human 14-3-3 ε.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
Conklin D.S., Proc. Natl. Acad. Sci. U.S.A. 92:7892-7896(1995). Jin D.-Y., Nature 382:308-308(1996). Chong S.S., ome Res. 6:735-741(1996).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total 14-3-3 ε protein.
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (By similarity). Positively regulates phosphorylated protein HSF1 nuclear export to the cytoplasm