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Home / Primary Antibodies / Polyclonal Antibodies

YME1L1 antibody

SKU : BHA10809537

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Mfr.No.	FNab09566
Alternative Names	FTSH ; FTSH1 ; Meg4 ; MEG4 ; PAMP ; YME1like1(S.cerevisiae) ; YME1likeprotein1 ; YME1L ; YME1L1
Background	YME1L1(ATP-dependent zinc metalloprotease) is also named as FTSH1, YME1L,Meg-4,PAMP. YME1L1 plays a phylogenetically conserved role in mitochondrial protein metabolism.It also ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from the accumulation of oxidatively damaged membrane proteins. YME1L1 can prevent mitochondrial DNA inserting into nuclear. It has 3 isoforms produced by alternative splicing with the molecular weight of 86 kDa, 80 kDa and 76 kDa.
Categories	Primary Antibodies
Cellular Localization	Mitochondrion Inner Membrane
Clonality	polyclonal
Description	Putative ATP-dependent protease which plays a role in mitochondrial protein metabolism. Ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from the accumulation of oxidatively damaged membrane proteins. Requires to control the accumulation of nonassembled respiratory chain subunits (NDUFB6, OX4 and ND1). Seems to act in the processing of OPA1.
Host	Rabbit
Immunogen	YME1-like 1
Isotype	IgG
Molecular Weight	86 kDa, 60 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Mitochondrion inner membrane
Synonyms	FTSH, FTSH1, Meg 4, MEG4, PAMP, YME1 like 1, YME1 like protein 1, YME1L, YME1L1

Uniprot	Q96TA2
Gene Id	10730
Research Area	Metabolism
Weight	86kDa,Observed 86kDa,60kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF

Dilution

WB	1:200-1:2000
IF	1:10-1:100
IHC	1:50-1:200

Tested Application

WB: 1:200-1:2000; IF: 1:10-1:100; IHC: 1:50-1:200

Manual	FNab09566.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809537	FNab09566	100ug	$260		Add to Cart

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