Plays an active role in the formation of cell surface protrusions downstream of activated PDGFB receptors. Plays an important role in actin-microspike formation through cooperation with WASL. May cooperate with WASP and WASL to induce mobilization and reorganization of the actin filament system.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Plays an active role in the formation of cell surface protrusions downstream of activated PDGFB receptors. Plays an important role in actin-microspike formation through cooperation with WASL. May cooperate with WASP and WASL to induce mobilization and reorganization of the actin filament system.
Host
Rabbit
Immunogen
WAS/WASL interacting protein family, member 2
Isotype
IgG
Molecular Weight
49 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
WICH, WIP related protein, WIPF2, WIRE
Uniprot
Q8TF74
Gene Id
147179
Research Area
Cardiovascular
Weight
46kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)