Component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored(TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting.
Categories
Primary Antibodies
Cellular Localization
Cytoplasm
Clonality
polyclonal
Description
Component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting.
Host
Rabbit
Immunogen
ubiquitin-like 4A
Isotype
IgG
Molecular Weight
18 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
Cytoplasm
Synonyms
DX254E, DXS254E, G6PD, GDX, ubiquitin like 4A, Ubiquitin like protein 4A, Ubiquitin like protein GDX, UBL4, UBL4A
Uniprot
P11441
Gene Id
8266
Research Area
Epigenetics, Metabolism
Weight
18kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)