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Home / Primary Antibodies

Ubiquitin Antibody (V8150SAF)

SKU : BHA17127265

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NSJ Bioreagents

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Mfr.No.	V8150SAF-100UG
Clonality	Recombinant Rabbit Monoclonal
Description	Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process, it is first activated by forming a thiol-ester complex with the activation component E1, which is then transferred to ubiquitin-carrier protein E2, followed by to ubiquitin ligase E3 for final delivery to epsilon-NH2 of the target protein lysine residue. IkB, p53, cdc25A, Bcl-2 etc. are shown as targets of ubiquitin-proteasome process as part of regulation of cell cycle progression, differentiation, cell stress response, and apoptosis. Moreover, ubiquitin have been reported to bind covalently with pathological inclusions which are resistant to degradation e.g. neurofibrillary tangles/paired helical filaments in Alzheimer's disease, Lewy bodies seen in Parkinson's disease, and Pick bodies found in Pick's disease etc.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Rabbit
Immunogen Region	A recombinant human partial protein (amino acids 1-119) was used as the immunogen for this recombinant Ubiquitin antibody.
Isotype	Rabbit IgG
Species Reactivity	Human
Note	Optimal dilution of the antibody should be determined by the researcher.

Uniprot	P0CG47

Format	Purified
Purity	Protein A affinity chromatography
Storage	Store the recombinant Ubiquitin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 1-2ug/ml

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/recombinant-ubiquitin-antibody-ubb-3143r-v8150" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127265	V8150SAF-100UG	100 ug	$499		Add to Cart

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