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Home / Primary Antibodies

Ubiquitin Antibody (V3934SAF)

SKU : BHA17125746

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NSJ Bioreagents

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Mfr.No.	V3934SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process, it is first activated by forming a thiol-ester complex with the activation component E1, which is then transferred to ubiquitin-carrier protein E2, followed by to ubiquitin ligase E3 for final delivery to epsilon-NH2 of the target protein lysine residue. IkB, p53, cdc25A, Bcl-2 etc. are shown as targets of ubiquitin-proteasome process as part of regulation of cell cycle progression, differentiation, cell stress response, and apoptosis. Moreover, ubiquitin have been reported to bind covalently with pathological inclusions which are resistant to degradation e.g. neurofibrillary tangles/paired helical filaments in Alzheimer's disease, Lewy bodies seen in Parkinson's disease, and Pick bodies found in Pick's disease etc.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A portion of amino acids 1-119 from the human protein was used as the immunogen for the Ubiquitin antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the Ubiquitin antibody should be determined by the researcher.

Uniprot	P0CG47, P0CG48, P62979, P62987, P62988

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the Ubiquitin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	WB, ELISA, IHC-P
Description	ELISA (order BSA/sodium azide-free format for coating),Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17125746	V3934SAF-100UG	100 ug	$499		Add to Cart

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