Rabbit Anti-Human TYRO3 (pTyr685 + pTyr686) Polyclonal

Mfr.No.	SPC-1093, SPC-1093D, SPC-1093D-A390, SPC-1093D-A488, SPC-1093D-A594, SPC-1093D-BI, SPC-1093D-FITC
Immunogen Species	Human
Alternative Names	Brt Antibody, BYK Antibody, DTK Antibody, RSE Antibody, SKY Antibody, Tif Antibody, tyro3 Antibody, TYRO3_HUMAN Antibody, Tyrosine-protein kinase byk Antibody, Tyrosine-protein kinase DTK Antibody, Tyrosine-protein kinase receptor TYRO3 Antibody, Tyrosine-protein kinase RSE Antibody, Tyrosine-protein kinase SKY Antibody
Categories	Antibodies
Cellular Localization	Cell membrane
Certificate Of Analysis	A 1:250 dilution of SPC-1093 was sufficient for detection of TYRO3 (pTyr685 + pTyr686) in 10 ug of mouse brain lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Description	Rabbit Anti-Human TYRO3 (pTyr685 + pTyr686) Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	A phospho-specific peptide corresponding to residues surrounding Tyr685 and Tyr686 of human Tyro3 (AA682-689), Homo Sapiens (Human)
Immunogen Region	A phospho-specific peptide corresponding to residues surrounding Tyr685 and Tyr686 of human Tyro3 (AA682-689)
Launch Date	2016/08/29
Net Weight (g)	0.1
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Human
Tissue Specificity	Highly expressed in the brain. Lower levels in other tissues.

Swissprot	Q06418
Accession Number	NP_006284
Gene Id	7301
Target	TYRO3 (pTyr685 + pTyr686)
Research Area	Cell adhesion, Cell Signaling, Membrane Proteins, Protein Phosphorylation, Tyrosine Kinases, Neuroscience, Cytoskeleton

Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Dilutions	WB (1:250); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	Highly expressed in the brain. Lower levels in other tissues.
Scientific Background	TYRO3 responds to TUB, TULP1, GAS6 and protein S as ligands and regulates cell survival, proliferation, immunoregulation, phagocytosis, cell migration, actin organization, spermatogenesis, platelet aggregation, clot stabilization, memory formation, circadian rhythm and synaptic plasticity. signalling transduction can occur via MAPK/ERK and Pi3K/AKT pathways. Overexpression by various cancers provide transformative ability and increased survival signals.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects 96.905 kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	AM, WB
Description	WB ; AM
Dilution	WB (1:250); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11914490-1	SPC-1093D	Unconjugated	100 ul	$331	Add to Cart
BHA11914490-2	SPC-1093D-A390	ATTO 390	100 ul	$385	Add to Cart
BHA11914490-3	SPC-1093D-A488	ATTO 488	100 ul	$384	Add to Cart
BHA11914490-4	SPC-1093D-A594	ATTO 594	100 ul	$384	Add to Cart
BHA11914490-5	SPC-1093D-BI	Biotin	100 ul	$380	Add to Cart
BHA11914490-6	SPC-1093D-FITC	FITC	100 ul	$375	Add to Cart

TYRO3 Antibody (pTyr685 + pTyr686) - SPC-1093