Rabbit Anti-Human Twist Polyclonal

Mfr.No.	SPC-1336, SPC-1336D, SPC-1336D-A390, SPC-1336D-A488, SPC-1336D-A594, SPC-1336D-BI, SPC-1336D-FITC
Immunogen Species	Human
Alternative Names	ACS3 Antibody, bHLHa38 Antibody, SCS Antibody, TWIST Antibody, Twist basic helix loop helix transcription factor 1 Antibody, Twist homolog 1 Antibody, Twist related protein 1 Antibody, TWIST1 Antibody
Categories	Antibodies
Cellular Localization	Nucleus
Certificate Of Analysis	A 1:1000 dilution of SPC-1336 was sufficient for detection of Twist in 10 ug of mouse muscle cell lysates by ECL immunoblot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Description	Rabbit Anti-Human Twist Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	Peptide sequence around aa.18~22(S-N-S-E-E) derived from Human Twist1, Homo Sapiens (Human)
Immunogen Region	Peptide sequence around aa.18~22(S-N-S-E-E) derived from Human Twist1
Isotype	IgG
Launch Date	2016/09/06
Net Weight (g)	0.1
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Mouse, Rat, Human
Tissue Specificity	Subset of mesodermal cells.

Swissprot	Q15672
Accession Number	NP_000465.1
Gene Id	7291
Target	Twist
Research Area	Cell Signaling, Epigenetics and Nuclear Signaling, Cancer, Cardiovascular System, Heart, Neuroscience

Buffer	PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide
Dilutions	WB (1:2000), IHC (1:200); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	Subset of mesodermal cells.
Scientific Background	TWIST1 is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. It has been implicated in cell lineage determination and differentiation. The strongest expression of this mRNA is in placental tissue, in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects ~21kDa, endogenous levels of total Twist1 protein.
Storage	-20ºC
Storage Buffer	PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	IHC, WB
Description	WB ; IHC
Dilution	WB (1:2000), IHC (1:200); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

Reference	1. Reinhold M.I., Kapadia R.M., Liao Z., Naski M.S. (2006) J Biol Chem. 281(3): 1381-1388.

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11918234-1	SPC-1336D	Unconjugated	100 ul	$286	Add to Cart
BHA11918234-2	SPC-1336D-A390	ATTO 390	100 ul	$340	Add to Cart
BHA11918234-3	SPC-1336D-A488	ATTO 488	100 ul	$339	Add to Cart
BHA11918234-4	SPC-1336D-A594	ATTO 594	100 ul	$339	Add to Cart
BHA11918234-5	SPC-1336D-BI	Biotin	100 ul	$334	Add to Cart
BHA11918234-6	SPC-1336D-FITC	FITC	100 ul	$330	Add to Cart

Twist Antibody - SPC-1336