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Home / Primary Antibodies / Polyclonal Antibodies

TRPV6 antibody

SKU : BHA10809022

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Mfr.No.	FNab09030
Alternative Names	ABP/ZF ; Calciumtransportprotein1 ; CaTL ; CaTlike ; CAT1 ; CATL ; ECAC2 ; Epithelialcalciumchannel2 ; HSA277909 ; LP6728 ; TRPV6
Background	Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine(PubMed:11097838, PubMed:11278579, PubMed:11248124 PubMed:15184369, PubMed:23612980). Important for normal Ca(2+) ion homeostasis in the body, including bone and skin(By similarity). The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification(PubMed:15184369). Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism; the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.
Categories	Primary Antibodies
Cellular Localization	Membrane
Clonality	polyclonal
Description	Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine (PubMed:11097838, PubMed:11278579, PubMed:11248124 PubMed:15184369, PubMed:23612980). Important for normal Ca(2+) ion homeostasis in the body, including bone and skin (By similarity). The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification (PubMed:15184369). Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)- calmodulin-dependent mechanism; the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.
Host	Rabbit
Immunogen	transient receptor potential cation channel, subfamily V, member 6
Isotype	IgG
Molecular Weight	82 kDa,70 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cell membrane
Synonyms	ABP/ZF, Calcium transport protein 1, CaT L, CaT like, CAT1, CATL, ECAC2, Epithelial calcium channel 2, HSA277909, LP6728, TRPV6, ZFAB

Uniprot	Q9H1D0
Gene Id	55503
Research Area	Cancer
Weight	82kDa,Observed 70kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IF, WB, IP

Description

ELISA ; IF ; WB ; IP

Dilution

WB	1:500-1:5000
IP	1:200-1:1000
IF	1:10-1:100

Tested Application

WB: 1:500-1:5000; IP: 1:200-1:1000; IF: 1:10-1:100

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809022	FNab09030	100ug	$260		Add to Cart

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