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Home / Primary Antibodies / Polyclonal Antibodies

TRPA1 antibody

SKU : BHA10809005

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Mfr.No.	FNab09013
Alternative Names	ANKTM1 ; TRPA1
Antigen	TRPA1
Background	The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Receptor-activated non-selective cation channel involved in detection of pain and possibly also in cold perception and inner ear function (PubMed:25389312, PubMed:25855297). Has a central role in the pain response to endogenous inflammatory mediators and to a diverse array of volatile irritants, such as mustard oil, cinnamaldehyde, garlic and acrolein, an irritant from tears gas and vehicule exhaust fumes (PubMed:25389312, PubMed:20547126). Is also activated by menthol (in vitro)(PubMed:25389312). Acts also as a ionotropic cannabinoid receptor by being activated by delta(9)-tetrahydrocannabinol (THC), the psychoactive component of marijuana (PubMed:25389312). May be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds. Probably operated by a phosphatidylinositol second messenger system (By similarity).
Host	Rabbit
Immunogen	transient receptor potential cation channel, subfamily A, member 1
Isotype	IgG
Molecular Weight	120 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	A synthetic peptide corresponding to a sequence within amino acids 850-950
Synonyms	ANKTM1, TRPA1

Uniprot	O75762
Gene Id	8989
Research Area	Neuroscience
Weight	127kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB

Description

ELISA ; WB

Dilution

WB	1:500-1:5000

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab09013.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809005	FNab09013	100ug	$280		Add to Cart

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