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Home / Primary Antibodies / Polyclonal Antibodies

TRIP10 antibody

SKU : BHA10808988

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Mfr.No.	FNab08996
Alternative Names	Cdc42interactingprotein4 ; CIP4 ; HSTP ; ProteinFelic ; Salttolerantprotein ; STOT ; STP ; TRinteractingprotein10 ; TRIP10 ; TRIP10
Background	Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling(By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N- WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
Host	Rabbit
Immunogen	thyroid hormone receptor interactor 10
Isotype	IgG
Molecular Weight	75-85 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	Cdc42 interacting protein 4, CIP4, HSTP, Protein Felic, Salt tolerant protein, STOT, STP, TR interacting protein 10, TRIP 10, TRIP10

Uniprot	Q15642
Gene Id	9322
Research Area	Signal Transduction
Weight	63kDa,Observed 85kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IF

Description

ELISA ; WB ; IF

Dilution

WB	1:500-1:5000
IP	1:500-1:5000
IF	1:10-1:100

Tested Application

WB: 1:500-1:5000; IP: 1:500-1:5000; IF: 1:10-1:100

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808988	FNab08996	100ug	$260		Add to Cart

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