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Home / Primary Antibodies / Polyclonal Antibodies

TRIM6 antibody

SKU : BHA10808983

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Mfr.No.	FNab08991
Alternative Names	RINGfingerprotein89 ; RNF89 ; TRIM6 ; tripartitemotifcontaining6
Background	E3 ubiquitin-protein ligase which ubiquitinates MYC and inhibits its transcription activation activity, maintaining the pluripotency of embryonic stem cells(By similarity). Involved in the synthesis of unanchored K48-linked polyubiquitin chains which interact with and activate the serine/threonine kinase IKBKE, leading to phosphorylation of STAT1 and stimulation of an antiviral response(PubMed:24882218).
Categories	Primary Antibodies
Cellular Localization	Cytoplasm
Clonality	polyclonal
Description	E3 ubiquitin-protein ligase which ubiquitinates MYC and inhibits its transcription activation activity, maintaining the pluripotency of embryonic stem cells (By similarity). Involved in the synthesis of unanchored K48-linked polyubiquitin chains which interact with and activate the serine/threonine kinase IKBKE, leading to phosphorylation of STAT1 and stimulation of an antiviral response (PubMed:24882218).
Host	Rabbit
Immunogen	tripartite motif-containing 6
Isotype	IgG
Molecular Weight	56 kDa
Reactivity	Human, Rat
Regulatory	RUO
Subcellular Location	Cytoplasm
Synonyms	RING finger protein 89, RNF89, TRIM6, tripartite motif containing 6

Uniprot	Q9C030
Gene Id	117854
Research Area	Metabolism
Weight	56kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IHC, WB

Description

ELISA ; IHC ; WB

Dilution

WB	1:500-1:5000
IHC	1:20-1:200

Tested Application

WB: 1:500-1:2000; IHC: 1:20-1:200

Manual	FNab08991.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808983	FNab08991	100ug	$260		Add to Cart

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