The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype.
Categories
Primary Antibodies
Clonality
polyclonal
Description
It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line.