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Home / Primary Antibodies / Polyclonal Antibodies

TRAP1 Antibody - SPC-209

BHA11907507
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+1 866.986.9598
Email
[email protected]
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Swissprot Q12931
Accession Number NP_057376.2
Gene Id 10131
Target TRAP1
Research Area Cancer, Heat Shock, Cell Signaling, Protein Trafficking
Buffer PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration 1 mg/ml
Dilutions WB (1:1000), ICC/IF (1:120); optimal dilutions for assays should be determined by the user.
Purification Protein A Purified
Scientific Background The 90 kDa heat shock protein (HSP90) family of molecular chaperones is a highly conserved family of proteins that play an important physiological role. HSP90 is involved in numerous cellular processes but is best known for its association with signal transduction machinery. A recently cloned homolog of HSP90 is the tumor necrosis factor receptor-associated protein (TRAP1). Like HSP90, TRAP1 is found to beassociated with numerous proteins involved in diverse actions (1, 2). Immunofluorescence data has shown TRAP1 to be localized in the mitochondria of mammalian cells. This observation and the fact that TRAP1 is shown to have a mitochondrial targeting presequence strongly implicates TRAP1 as a mitochondrial matrix protein (3).
Shipping Temperature Blue Ice or 4°C
Specificity Detects ~75 kDa, multiple isoforms.
Storage -20ºC
Storage Buffer PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Storage Temperature -20°C
Applications WB, ICC/IF
Description WB ; ICC ; IF
Dilution WB (1:1000), ICC/IF (1:120); optimal dilutions for assays should be determined by the user.
Product Manual SDS
SDS
Reference 1. Felts S.J., et al. (2000) J Biol Chem. 275(5): 3305-3312.

2. Costantino E., et al. (2009) Cancer Lett. 279(1): 39-46.

3. Cechetto J.D., Gupta R.S. (2000) Exp Cell Res. 260(1): 30-39.
Combination SKU Supplier No. Conjugate Size Your price Quantity
BHA11907507-1 SPC-209D Unconjugated 100 ug $306
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BHA11907507-2 SPC-209D-A390 ATTO 390 100 ug $360
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BHA11907507-3 SPC-209D-A488 ATTO 488 100 ug $359
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BHA11907507-4 SPC-209D-A594 ATTO 594 100 ug $359
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BHA11907507-5 SPC-209D-ALP Alkaline Phosphatase 100 ug $352
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BHA11907507-6 SPC-209D-APC APC 100 ug $358
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BHA11907507-7 SPC-209D-BI Biotin 100 ug $354
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BHA11907507-8 SPC-209D-FITC FITC 100 ug $350
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BHA11907507-9 SPC-209D-HRP HRP 100 ug $345
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BHA11907507-10 SPC-209D-PCP PerCP 100 ug $358
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BHA11907507-11 SPC-209D-RPE RPE 100 ug $355
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BHA11907507-12 SPC-209S Unconjugated 12 ug $44
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