Mouse Anti-Human TNFRSF18 Monoclonal IgG2b

Mfr.No.	SMC-556, SMC-556D, SMC-556D-A390, SMC-556D-A488, SMC-556D-A594, SMC-556D-ALP, SMC-556D-APC, SMC-556D-BI, SMC-556D-FITC, SMC-556D-HRP, SMC-556D-PCP, SMC-556D-RPE, SMC-556S
Immunogen Species	Human
Alternative Names	Activation inducible TNFR family receptor antibody, AITR antibody, CD357 antibody, GITR antibody, GITRD antibody, Glucocorticoid induced TNFR related protein antibody, glucocorticoid-induced tnf receptor ligand antibody, Glucocorticoid-induced TNFR-related protein antibody, TNF receptor superfamily activation inducible protein antibody, TNFRSF 18 antibody, TNR18_HUMAN antibody, Tumor necrosis factor receptor superfamily member 18 antibody, Tumor necrosis factor receptor superfamily member 18 precursor antibody
Antigen	TNFRSF18
Categories	Antibodies
Cellular Localization	Cell membrane, Secreted
Certificate Of Analysis	A 1:1000 dilution of SMC-556 was sufficient for detection of Tumor Necrosis Factor Receptor Superfamily, Member 18 in 15 ug of Mouse Skeletal Muscle by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Clonality	Monoclonal
Conjugate	Unconjugated, ATTO 390, ATTO 488, ATTO 594, Alkaline Phosphatase, APC, Biotin, FITC, HRP, PerCP, RPE
Description	Mouse Anti-Human TNFRSF18 Monoclonal IgG2b
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Mouse
Gross Weight (kg)	1.4
Immunogen	Synthetic peptide from the C-terminal of Human Tumor Necrosis Factor Receptor Superfamily, Member 18, Homo Sapiens (Human)
Immunogen Region	Synthetic peptide from the C-terminal of Human Tumor Necrosis Factor Receptor Superfamily, Member 18
Isotype	IgG2b
Launch Date	2018/11/21
Net Weight (g)	0.1
Reactivity	Human, Mouse
Species Reactivity Medium	Mouse, Human
Tissue Specificity	Expressed in lymph node, peripheral blood leukocytes and weakly in spleen.

Swissprot	Q9Y5U5
Accession Number	NP_004186.1
Gene Id	8784
Target	TNFRSF18
Clone No	T9P4G4-D7
Research Area	Cell Signaling, Growth Factors, TNF, Immunology, Innate Immunity, Cytokines, TNF Superfamily, Cancer

Concentration	1 mg/ml
Purification	Protein G Purified
Scientific Background	TNFRSF18 is a member of the tumor necrosis factor receptor (TNF-R) superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25+/CD4+ regulatory T cells (1), and could be a suitable molecular target for preventing or treating automimmune diseases (2).
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects 25 kDa.
Storage Buffer	PBS pH 7.4, 50% glycerol, 0.09% Sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	ELISA, IHC, WB
Dilution	WB (1:1000); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
Conjugate Datasheet
SDS

Reference	1. "Entrez Gene: TNFRSF18 tumor necrosis factor receptor superfamily, member 18". 2. Shimizu J. et al., (2002) Nat. Immunol. 3(2): 135-142.

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11920107-1	SMC-556D	Unconjugated	100 ug	$330	Add to Cart
BHA11920107-2	SMC-556D-A390	ATTO 390	100 ug	$384	Add to Cart
BHA11920107-3	SMC-556D-A488	ATTO 488	100 ug	$383	Add to Cart
BHA11920107-4	SMC-556D-A594	ATTO 594	100 ug	$383	Add to Cart
BHA11920107-5	SMC-556D-ALP	Alkaline Phosphatase	100 ug	$376	Add to Cart
BHA11920107-6	SMC-556D-APC	APC	100 ug	$382	Add to Cart
BHA11920107-7	SMC-556D-BI	Biotin	100 ug	$378	Add to Cart
BHA11920107-8	SMC-556D-FITC	FITC	100 ug	$374	Add to Cart
BHA11920107-9	SMC-556D-HRP	HRP	100 ug	$370	Add to Cart
BHA11920107-10	SMC-556D-PCP	PerCP	100 ug	$382	Add to Cart
BHA11920107-11	SMC-556D-RPE	RPE	100 ug	$380	Add to Cart
BHA11920107-12	SMC-556S	Unconjugated	12 ug	$44	Add to Cart

TNFRSF18 Antibody, Clone T9P4G4-D7 - SMC-556

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