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Home / Primary Antibodies / Polyclonal Antibodies

TNF alpha Antibody - SPC-1315

BHA11917856
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Contact us to order
Tel
+1 866.986.9598
Email
[email protected]
Get a Quote
Ask Merchant
Request More Infos
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Swissprot P01375
Accession Number NP_000585.2
Gene Id 7124
Target TNF alpha
Research Area Immunology, Innate Immunity, Cytokines, TNF Superfamily, Cardiovascular System, Atherosclerosis, Vascular Inflammation, Inflammatory Mediators, Cell Signaling, Growth Factors, TNF, Metabolism, Cancer
Buffer PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide
Dilutions IHC (1:100), ICC/IF (1:500), ELISA (1:10000); optimal dilutions for assays should be determined by the user.
Purification Peptide Affinity Purified
Scientific Background Tumor necrosis factor is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. The primary role of TNF is in the regulation of immune cells. TNF, being an endogenous pyrogen, is able to induce fever, apoptotic cell death, cachexia, inflammation and to inhibit tumorigenesis and viral replication and respond to sepsis via IL1 & IL6 producing cells. Dysregulation of TNF production has been implicated in a variety of human diseases including Alzheimer's disease, cancer, major depression, Psoriasis and inflammatory bowel disease (IBD).
Shipping Temperature Blue Ice or 4°C
Specificity Detects endogenous levels of total TNFA protein.
Storage -20ºC
Storage Buffer PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide *Storage buffer may change when conjugated
Storage Temperature -20°C
Applications ELISA, IHC, ICC/IF
Description IHC ; ICC ; IF ; ELISA
Dilution IHC (1:100), ICC/IF (1:500), ELISA (1:10000); optimal dilutions for assays should be determined by the user.
Product Manual SDS
SDS
Reference 1. Swardfager W et al. (2010) Biol Psychiatry 68 (10): 930–941.

2. Locksley RM et al. (2001) Cell 104 (4): 487–501.

3. Dowlati Y et al. (2010) Biol Psychiatry 67 (5): 446–457.

4. Victor FC and Gottlieb AB (2002) J Drugs Dermatol 1 (3): 264–75.

5. Brynskov J. (2002) Gut 51 (1): 37–43.
Combination SKU Supplier No. Conjugate Size Your price Quantity
BHA11917856-1 SPC-1315D Unconjugated 100 ul $286
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BHA11917856-2 SPC-1315D-A390 ATTO 390 100 ul $340
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BHA11917856-3 SPC-1315D-A488 ATTO 488 100 ul $339
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BHA11917856-4 SPC-1315D-A594 ATTO 594 100 ul $339
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BHA11917856-5 SPC-1315D-BI Biotin 100 ul $334
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BHA11917856-6 SPC-1315D-FITC FITC 100 ul $330
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