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Home / Primary Antibodies / Monoclonal Antibodies

TMEM173 antibody

SKU : BHA10810738

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Mfr.No.	FNab10949
Background	This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
Clonality	polyclonal
Host	Mouse
Immunogen	transmembrane protein 173
Immunogen Region	Beta-casein
Isotype	IgG2b
Molecular Weight	39 kDa
Reactivity	Human
Recommended Dilution	WB: 1:500-1:2000; IHC: 1:50-1:200
Synonyms	ERIS, hMITA, hSTING, MITA, MPYS, NET23, SAVI, STING

Uniprot	Q86WV6
Gene Id	340061
Clone No	1G9

Form	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:1000 - 1:5000; IHC: 1:100 - 1:500

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10616.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810738	FNab10949	100ug	$300		Add to Cart

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