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Home / Primary Antibodies / Polyclonal Antibodies

TLR3 antibody

SKU : BHA10808718

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Mfr.No.	FNab08726
Background	Key component of innate and adaptive immunity. TLRs(Toll-like receptors) control host immune response against pathogens through recognition of molecular pattes specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular pattes specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response.
Host	Rabbit
Immunogen	toll-like receptor 3
Isotype	IgG
Reactivity	Human, Mouse, Rat
Regulatory	RUO

Antigen	TLR3
Uniprot	O15455
Gene Id	7098
Research Area	Developmental biology, Immunology, Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC
Description	ELISA ; IHC
Tested Application	IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808718	FNab08726	100ug	$260		Add to Cart

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