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Home / Primary Antibodies / Polyclonal Antibodies

TLR3 antibody

SKU : BHA10808718

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Mfr.No.	FNab08726
Background	Key component of innate and adaptive immunity. TLRs(Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response.
Host	Rabbit
Immunogen	toll-like receptor 3
Isotype	IgG
Reactivity	Human, Mouse, Rat
Regulatory	RUO

Uniprot	O15455
Gene Id	7098
Research Area	Developmental biology, Immunology, Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC
Description	ELISA ; IHC
Tested Application	IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808718	FNab08726	100ug	$260		Add to Cart

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