Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source.
Categories
Primary Antibodies
Clonality
monoclonal
Description
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source.
Host
Mouse
Immunogen
translocase of inner mitochondrial membrane 44 homolog(yeast)
Isotype
IgG1
Molecular Weight
45 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
MIMT44, TIM44
Uniprot
O43615
Gene Id
10469
Clone No
0E2
Research Area
Signal Transduction, Metabolism
Form
liquid
Format
liquid
Purification
Protein A+G purification
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)