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Home / Primary Antibodies / Polyclonal Antibodies

TGS1 antibody

SKU : BHA10808646

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Mfr.No.	FNab08654
Alternative Names	HCA137 ; NCOA6IP ; PIMT
Categories	Primary Antibodies
Clonality	polyclonal
Description	Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation.
Host	Rabbit
Immunogen	trimethylguanosine synthase homolog
Isotype	IgG
Molecular Weight	97 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	HCA137, NCOA6IP, PIMT

Uniprot	Q96RS0
Gene Id	96764
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab08654.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808646	FNab08654	100ug	$260		Add to Cart

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