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Home / Primary Antibodies / Polyclonal Antibodies

TGF-beta 3 antibody

SKU : BHA10808632

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Mfr.No.	FNab08640
Background	This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	transforming growth factor, beta 3
Isotype	IgG
Molecular Weight	45KD
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	ARVD, ARVD1, LDS5, RNHF, TGF-beta3

Uniprot	P10600
Gene Id	7043
Research Area	Developmental biology, Immunology, Cardiovascular, Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Manual	FNab08640.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808632	FNab08640	100ug	$260		Add to Cart

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