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Home / Primary Antibodies / Polyclonal Antibodies

TCHP antibody

SKU : BHA10808549

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Mfr.No.	FNab08557
Background	Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells(PubMed:15731013, PubMed:18931701). Is a negative regulator of ciliogenesis(PubMed:25270598).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (PubMed:15731013, PubMed:18931701). Is a negative regulator of ciliogenesis (PubMed:25270598).
Host	Rabbit
Immunogen	trichoplein, keratin filament binding
Isotype	IgG
Molecular Weight	61 kDa
Reactivity	Human
Regulatory	RUO

Uniprot	Q9BT92
Gene Id	84260
Research Area	Cancer

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500-1:2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808549	FNab08557	100ug	$280		Add to Cart

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