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Home / Primary Antibodies / Polyclonal Antibodies

TCEB3 antibody

SKU : BHA10808542

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Mfr.No.	FNab08550
Background	This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
Categories	Primary Antibodies
Clonality	polyclonal
Description	SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
Host	Rabbit
Immunogen	transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
Isotype	IgG
Molecular Weight	105 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO

Uniprot	Q14241
Gene Id	6924
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IF, WB
Description	ELISA ; IF ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab08550.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808542	FNab08550	100ug	$260		Add to Cart

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