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Home / Primary Antibodies / Polyclonal Antibodies

TBC1D17 antibody

SKU : BHA10808502

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Mfr.No.	FNab08510
Background	Probable GTPase-activating protein for Rab8; its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor(TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment(ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50; the function requires its catalytic activity, however, the involved Rab is not known.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Probable GTPase-activating protein for Rab8; its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor (TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment (ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50; the function requires its catalytic activity, however, the involved Rab is not known.
Host	Rabbit
Immunogen	TBC1 domain family, member 17
Isotype	IgG
Molecular Weight	73-100 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	TBC1 domain family member 17, TBC1 domain family, member 17, TBC1D17

Uniprot	Q9HA65
Gene Id	79735
Research Area	Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IF, IHC
Description	ELISA ; WB ; IF ; IHC
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808502	FNab08510	100ug	$260		Add to Cart

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