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Home / Primary Antibodies / Monoclonal Antibodies

TARP Gamma2/4/8 (Stargazin) Antibody, Clone S245-36 - SMC-422

BHA11903925
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+1 866.986.9598
Email
[email protected]
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Swissprot Q71RJ2
Accession Number NP_445803.1
Gene Id 84347
Target Stargazin
Clone No S245-36
Research Area Ion Channels, Calcium Channels, Voltage-Gated Calcium Channels, Cell Markers, Neuron Markers, Postsynaptic Markers, Neuroscience
Buffer PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration 1 mg/ml
Dilutions WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification Protein G Purified
Scientific Background Stargazin belongs to a group called voltage gated calcium channels (VGCCs) which are present in most excitable cells. Stargazin is thought to stabilize the calcium channel in an inactivated (closed) state. There are five high voltage activated calcium channel types (L, N, P, Q, and R) and one low voltage activated channel type (T). Each of these channels exists as a heteromultimer of a1, b, a2/ d and g subunits with the voltage activated calcium channel function carried by the a subunits. VGCCs exert spatial and temporal control over cellular calcium concentrations and serve to modulate neurotransmitter release, hormone secretion, muscle contraction, electrical activity, cell metabolism and proliferation, gene expression, and neuronal survival.
Shipping Temperature Blue Ice or 4°C
Specificity Detects ~35-55kDa. Does not cross-react with TARPGamma3.
Storage -20ºC
Storage Buffer PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Storage Temperature -20°C
Applications WB, ICC/IF
Description WB ; ICC ; IF
Dilution WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Product Manual SDS
SDS
Reference 1. Gill M.B., et al. (2011) J Neurosci. 31(18): 6928-6938.

2. Yu L. (2011) Neuroscience. 178: 13-20.

3. Steinmetz C.C., Turrigiano G.G. (2010) J Neurosci. 30: 14685-14690.

4. Kato. A.S. et al. (2007) J Neurosci. 27: 4969-4977.

5. Letts V.A., et al. (1998) Nat Genet. 19: 340-34
Combination SKU Supplier No. Conjugate Size Your price Quantity
BHA11903925-1 SMC-422D Unconjugated 100 ug $330
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BHA11903925-2 SMC-422D-A390 ATTO 390 100 ug $384
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BHA11903925-3 SMC-422D-A488 ATTO 488 100 ug $383
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BHA11903925-4 SMC-422D-A594 ATTO 594 100 ug $383
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BHA11903925-5 SMC-422D-ALP Alkaline Phosphatase 100 ug $376
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BHA11903925-6 SMC-422D-APC APC 100 ug $382
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BHA11903925-7 SMC-422D-BI Biotin 100 ug $378
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BHA11903925-8 SMC-422D-FITC FITC 100 ug $374
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BHA11903925-9 SMC-422D-HRP HRP 100 ug $370
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BHA11903925-10 SMC-422D-PCP PerCP 100 ug $382
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BHA11903925-11 SMC-422D-RPE RPE 100 ug $380
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BHA11903925-12 SMC-422S Unconjugated 12 ug $44
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