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Home / Primary Antibodies / Polyclonal Antibodies

Stathmin antibody

SKU : BHA10808302

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Mfr.No.	FNab08310
Alternative Names	C1orf215 ; FLJ32206 ; Lag ; LAP18 ; Metablastin ; Oncoprotein18 ; OP18 ; Phosphoproteinp19 ; PP17 ; PP19 ; PR22
Background	This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Stathmin 1 (STMN1) normally regulates microtubule dynamics either by sequestering free tubulin heterodimers or by promoting microtubule catastrophe. STMN1 is highly expressed in fetal and adult brain, spinal cord, and cerebellum. Many different phosphorylated forms are observed depending on specific combinations among the sites which can be phosphorylated. Phosphorylation of stathmin is involved in response to NGF, neuron polarization and microtubule polymerization inhibition activity. Increased expression of STMN1 has been observed in a variety of human malignancies, such as colorectal primary tumors and metastatic tissues, but its association with melanoma is so far not well known.
Host	Rabbit
Immunogen	stathmin 1/oncoprotein 18
Isotype	IgG
Molecular Weight	Refer to figures
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	C1orf215, FLJ32206, Lag, LAP18, Metablastin, Oncoprotein 18, OP18, Phosphoprotein p19, PP17, PP19, PR22, Prosolin, Protein Pr22, SMN, Stathmin, stathmin 1/oncoprotein 18, Stathmin1, STMN1

Uniprot	P16949
Gene Id	3925
Research Area	Signal Transduction, Neuroscience
Weight	18 kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF

Dilution

WB	1:200-1:2000

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Manual	FNab08310.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808302	FNab08310	100ug	$260		Add to Cart

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