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Home / Primary Antibodies / Polyclonal Antibodies

SPO11 antibody

SKU : BHA10808176

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Mfr.No.	FNab08184
Background	Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms the double-strand breaks(DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles. Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles. Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2.
Host	Rabbit
Immunogen	SPO11 meiotic protein covalently bound to DSB homolog
Isotype	IgG
Molecular Weight	55-70 kDa
Reactivity	Human, Mouse
Regulatory	RUO

Uniprot	Q9Y5K1
Gene Id	23626
Research Area	Developmental biology, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500-1:2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808176	FNab08184	100ug	$280		Add to Cart

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