Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate(SPP), a lipid mediator with both intra-and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro- dihydrosphingosine, D-erythro-sphingosine and L-threo- dihydrosphingosine. Binds phosphoinositides.
Host
Rabbit
Immunogen
sphingosine kinase 2
Isotype
IgG
Molecular Weight
65-70 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Uniprot
Q9NRA0
Gene Id
56848
Research Area
Cardiovascular, Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)