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Home / Primary Antibodies / Polyclonal Antibodies

SNX17 antibody

SKU : BHA10808076

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Mfr.No.	FNab08084
Alternative Names	KIAA0064
Background	Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate(PtdIns(3P)).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).
Host	Rabbit
Immunogen	sorting nexin 17
Isotype	IgG
Molecular Weight	52 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	KIAA0064

Uniprot	Q15036
Gene Id	9784
Research Area	Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IF, IHC, IP
Description	ELISA ; WB ; IF ; IHC ; IP
Tested Application	WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:20-1:200

Manual	FNab08084.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808076	FNab08084	100ug	$260		Add to Cart

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