Histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di-and tri-methylation, but not monomethylation(PubMed:15235609, PubMed:22419068). Also methylates 'Lys-5' of histone H4(PubMed:22419068). Plays an important role in transcriptional activation as a member of an RNA polymerase complex(PubMed:15235609). Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences(PubMed:15235609).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Histone methyltransferase. Specifically methylates 'Lys- 4' of histone H3, inducing di- and tri-methylation, but not monomethylation (PubMed:15235609, PubMed:22419068). Also methylates 'Lys-5' of histone H4 (PubMed:22419068). Plays an important role in transcriptional activation as a member of an RNA polymerase complex (PubMed:15235609). Binds DNA containing 5'- CCCTCC-3' or 5'-GAGGGG-3' sequences (PubMed:15235609).
Host
Rabbit
Immunogen
SET and MYND domain containing 3
Isotype
IgG
Molecular Weight
42-45 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
ZMYND1, ZNFN3A1
Uniprot
Q9H7B4
Gene Id
64754
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)