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Home / Primary Antibodies / Polyclonal Antibodies

SMG5 antibody

SKU : BHA10808017

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Mfr.No.	FNab08025
Alternative Names	EST1B ; KIAA1089
Background	Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A(PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity.
Host	Rabbit
Immunogen	Smg-5 homolog, nonsense mediated mRNA decay factor
Isotype	IgG
Molecular Weight	114 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	EST1 like protein B, EST1B, hSMG 5, KIAA1089, LPTS interacting protein, LPTS RP1, LPTSRP1, Protein SMG5, RP11 54H19.7, SMG 5, SMG 5 homolog, SMG5

Uniprot	Q9UPR3
Gene Id	23381
Research Area	Epigenetics

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500-1:2000

Manual	FNab08025.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808017	FNab08025	100ug	$260		Add to Cart

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