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Home / Primary Antibodies / Polyclonal Antibodies

SECISBP2 antibody

SKU : BHA10807687

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Mfr.No.	FNab07695
Alternative Names	SBP2
Background	The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. Alternate splicing results in multiple transcript variants.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Binds to the SECIS element in the 3'-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB.
Host	Rabbit
Immunogen	SECIS binding protein 2
Isotype	IgG
Molecular Weight	110 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	SBP2

Uniprot	Q96T21
Gene Id	79048
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IP, IF
Description	ELISA ; WB ; IP ; IF
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Manual	FNab07695.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807687	FNab07695	100ug	$260		Add to Cart

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