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Home / Primary Antibodies / Polyclonal Antibodies

SDHA antibody

SKU : BHA10807661

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Mfr.No.	FNab07669
Alternative Names	SDH2 ; SDHF
Background	This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (PubMed:24781757). Can act as a tumor suppressor (PubMed:20484225).
Host	Rabbit
Immunogen	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
Isotype	IgG
Molecular Weight	70 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	SDH2, SDHF

Uniprot	P31040
Gene Id	6389
Research Area	Developmental biology, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IF, IP
Description	ELISA ; WB ; IHC ; IF ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100

Manual	FNab07669.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807661	FNab07669	100ug	$260		Add to Cart

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