Transmembrane protein 101; Putative NF-kappa-B-activating protein 130; TMEM101;
Antigen
SDC1
Categories
Primary Antibodies
Clonality
polyclonal
Description
Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.Lories V., J. Biol. Chem. 267:1116-1122(1992).Mali M., J. Biol. Chem. 265:6884-6889(1990).Mennerich D., Eur. J. Cancer 40:1373-1382(2004)
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human SDC1.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.
Lories V., J. Biol. Chem. 267:1116-1122(1992). Mali M., J. Biol. Chem. 265:6884-6889(1990). Mennerich D., Eur. J. Cancer 40:1373-1382(2004)
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total SDC1 protein.
Subcellular Location
Membrane, Single-pass type I membrane protein, Secreted, Secreted, exosome
Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP
Protein Families
Syndecan proteoglycan family
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.