Binds to TGFBR2 and activates TGFB signaling. In lung cancer cells, could serve as an endogenous autocrine and paracrine ligand of TGFBR2, which could regulate TGFBR2 signaling and hence modulate epithelial-mesenchymal transition and cancer progression.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Binds to TGFBR2 and activates TGFB signaling. In lung cancer cells, could serve as an endogenous autocrine and paracrine ligand of TGFBR2, which could regulate TGFBR2 signaling and hence modulate epithelial-mesenchymal transition and cancer progression.
Host
Rabbit
Immunogen
signal peptide, CUB domain, EGF-like 3
Isotype
IgG
Molecular Weight
130 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
CEGF3
Uniprot
Q8IX30
Gene Id
222663
Research Area
Developmental biology, Cardiovascular, Signal Transduction, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)