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Home / Primary Antibodies / Polyclonal Antibodies

RUNX1T1 antibody

SKU : BHA10807527

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Mfr.No.	FNab07535
Alternative Names	AML1T1 ; CBFA2T1 ; CDR ; ETO ; MTG8 ; ZMYND2
Background	Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes(PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner(PubMed:23251453). Can repress transactivation mediated by TCF12(PubMed:16803958). Acts as a negative regulator of adipogenesis(By similarity). The AML1-MTG8/ETO fusion protein frequently found in leukemic cells is involved in leukemogenesis and contributes to hematopoietic stem/progenitor cell self-renewal(PubMed:23812588).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes (PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner (PubMed:23251453). Can repress transactivation mediated by TCF12 (PubMed:16803958). Acts as a negative regulator of adipogenesis (By similarity). The AML1-MTG8/ETO fusion protein frequently found in leukemic cells is involved in leukemogenesis and contributes to hematopoietic stem/progenitor cell self-renewal (PubMed:23812588).
Host	Rabbit
Immunogen	runt-related transcription factor 1; translocated to, 1(cyclin D-related)
Isotype	IgG
Molecular Weight	70-75 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2

Uniprot	Q06455
Gene Id	862
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807527	FNab07535	100ug	$260		Add to Cart

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