Rabbit Anti-Human RSK1 (pThr573) Polyclonal

Mfr.No.	SPC-1078, SPC-1078D, SPC-1078D-A390, SPC-1078D-A488, SPC-1078D-A594, SPC-1078D-BI, SPC-1078D-FITC
Immunogen Species	Human
Alternative Names	RPS6KA1 Antibody, RSK 1 Antibody, RSK 1 p90 Antibody, RSK Antibody, RSK-1 Antibody, S6K alpha 1 Antibody, S6K-alpha-1 Antibody, 90 kDa ribosomal protein S6 kinase 1 Antibody, Ribosomal protein S6 kinase 90kD 1 Antibody, Ribosomal protein S6 kinase 90kDa polypeptide 1 Antibody, Ribosomal protein S6 kinase alpha 1 Antibody, Ribosomal protein S6 kinase alpha-1 Antibody, Ribosomal protein S6 kinase polypeptide 1 Antibody, Ribosomal S6 kinase 1 Antibody, RPS6K1 alpha Antibody, rps6ka Antibody, EC 2.7.11.1 Antibody, HU 1 Antibody, HU1 Antibody, KS6A1_HUMAN Antibody, MAP kinase activated protein kinase 1a Antibody, MAP kinase-activated protein kinase 1a Antibody, MAPK-activated protein kinase 1a Antibody, MAPKAP kinase 1a Antibody, MAPKAPK-1a Antibody, MAPKAPK1A Antibody, MGC79981 Antibody, Mitogen-activated protein kinase-activated protein kinase 1A Antibody, OTTHUMP00000004113 Antibody, p90 RSK1 Antibody, p90-RSK 1 Antibody, p90rsk Antibody, p90RSK1 Antibody, p90S6K Antibody, pp90RSK1 Antibody
Categories	Antibodies
Cellular Localization	Nucleus, Cytoplasm
Certificate Of Analysis	A 1:250 dilution of SPC-1078 was sufficient for detection of RSK1 (pThr573) in 10 ug of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Description	Rabbit Anti-Human RSK1 (pThr573) Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	A phospho-specific peptide corresponding to residues surrounding Thr573 of human RSK1 (AA570-576), Homo Sapiens (Human)
Immunogen Region	A phospho-specific peptide corresponding to residues surrounding Thr573 of human RSK1 (AA570-576)
Launch Date	2016/08/29
Net Weight (g)	0.1
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Human
Tissue Specificity	Widely expressed with higher expression in lympocytes, granulocytes, leukocytes, macrophages, blood, and cerebrospinal fluid cells.

Swissprot	Q15418
Accession Number	NP_002944
Gene Id	6195
Target	RSK1 (pThr573)
Research Area	Cell Signaling, Protein Phosphorylation, Serine / Threonine Kinases, MAPK Pathway, Epigenetics and Nuclear Signaling, Transcription

Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Dilutions	WB (1:250); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	Widely expressed with higher expression in lympocytes, granulocytes, leukocytes, macrophages, blood, and cerebrospinal fluid cells.
Scientific Background	RSK1 is a RSK (ribosomal S6 kinase) family of serine/threonine kinases. RSK1 contains 2 nonidentical kinase catalytic domains. RSK1 is known phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway -- a pro-growth/anti-apoptotic pathway, as it will activate CREB, which in turn will upregulate expression of cylin-D and c-Myc. Activation of this pathway is common in various types of tumours. In some cases, such breast and prostate cancer, upreguation of RSK has been shown in some patients.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects 82.723 kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	AM, WB
Description	WB ; AM
Dilution	WB (1:250); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11914220-1	SPC-1078D	Unconjugated	100 ul	$331	Add to Cart
BHA11914220-2	SPC-1078D-A390	ATTO 390	100 ul	$385	Add to Cart
BHA11914220-3	SPC-1078D-A488	ATTO 488	100 ul	$384	Add to Cart
BHA11914220-4	SPC-1078D-A594	ATTO 594	100 ul	$384	Add to Cart
BHA11914220-5	SPC-1078D-BI	Biotin	100 ul	$380	Add to Cart
BHA11914220-6	SPC-1078D-FITC	FITC	100 ul	$375	Add to Cart

RSK1 Antibody (pThr573) - SPC-1078

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