Rabbit Anti-Human ROS Polyclonal

Mfr.No.	SPC-1198, SPC-1198D, SPC-1198D-A390, SPC-1198D-A488, SPC-1198D-A594, SPC-1198D-BI, SPC-1198D-FITC
Immunogen Species	Human
Alternative Names	c ros antibody, c ros oncogene 1 receptor tyrosine kinase antibody, c ros1 antibody, MCF 3 antibody, MCF3 antibody, Proto oncogene c ros 1 protein antibody, Proto oncogene c Ros antibody, Ros 1 antibody, ROS 1C antibody, ROS antibody, ROS_HUMAN antibody, ROS1 antibody, ROS1C antibody, Transmembrane tyrosine specific protein kinase antibody, v ros avian UR2 sarcoma virus oncogene homolog 1 antibody, v ros UR2 sarcoma virus oncogene homolog 1 antibody
Categories	Antibodies
Cellular Localization	Membrane
Certificate Of Analysis	A 1:250 dilution of SPC-1198 was sufficient for detection of ROS in 10 ug of 293T cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Description	Rabbit Anti-Human ROS Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	Synthetic peptide of human ROS (AA1924-1938), Homo Sapiens (Human)
Immunogen Region	Synthetic peptide of human ROS (AA1924-1938)
Launch Date	2016/08/29
Net Weight (g)	0.1
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Human
Tissue Specificity	Expressed in brain. Expression is increased in primary gliomas.

Swissprot	P08922
Accession Number	NP_002935
Gene Id	6098
Target	ROS
Research Area	Cell Signaling, Protein Phosphorylation, Tyrosine Kinases, Receptor Tyrosine Kinases, Epigenetics and Nuclear Signaling, Cancer, Tumor Biomarkers, Oncoproteins, Growth Factor Receptors

Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Dilutions	WB (1:250); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	Expressed in brain. Expression is increased in primary gliomas.
Scientific Background	ROS1 is a receptor-tyrosine kinase that is activated upon binding an unidentified ligand. It has been suggested to activate several downstream signalling pathways in cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signalling pathway. Ros1 is highly expressed in several human cancers. However, its pattern of diverse mutations in human tumours is characteristic of a tumour suppressor protein.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects 263.915 kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	AM, WB
Description	WB ; AM
Dilution	WB (1:250); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11916362-1	SPC-1198D	Unconjugated	100 ul	$331	Add to Cart
BHA11916362-2	SPC-1198D-A390	ATTO 390	100 ul	$385	Add to Cart
BHA11916362-3	SPC-1198D-A488	ATTO 488	100 ul	$384	Add to Cart
BHA11916362-4	SPC-1198D-A594	ATTO 594	100 ul	$384	Add to Cart
BHA11916362-5	SPC-1198D-BI	Biotin	100 ul	$380	Add to Cart
BHA11916362-6	SPC-1198D-FITC	FITC	100 ul	$375	Add to Cart

ROS Antibody - SPC-1198