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Home / Primary Antibodies / Polyclonal Antibodies

RIP3 antibody

SKU : BHA10807304

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Mfr.No.	FNab07312
Background	Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	receptor-interacting serine-threonine kinase 3
Isotype	IgG
Molecular Weight	57 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	Receptor interacting protein 3, RIP 3, RIP like protein kinase 3, RIP3, RIPK3

Uniprot	Q9Y572
Research Area	Signal Transduction, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IP, WB
Description	ELISA ; IP ; WB
Tested Application	WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:100-1:400

Manual	FNab07312.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807304	FNab07312	100ug	$280		Add to Cart

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