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Home / Primary Antibodies / Polyclonal Antibodies

RHOB antibody

SKU : BHA10807274

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Mfr.No.	FNab07282
Alternative Names	ARH6 ; ARHB
Background	RHOB (ras homolog family member B) is a protein-coding gene. GO annotations related to this gene include GDP binding and GTP binding. An important paralog of this gene is RND1.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.
Host	Rabbit
Immunogen	ras homolog gene family, member B
Isotype	IgG
Molecular Weight	22 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	ARH6, ARHB

Uniprot	P62745
Gene Id	388
Research Area	Developmental biology, Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IF, IHC, IP
Description	ELISA ; WB ; IF ; IHC ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Manual	FNab07282.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807274	FNab07282	100ug	$260		Add to Cart

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