Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis. Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Has low intrinsic GTPase activity.
Clonality
polyclonal
Host
Rabbit
Immunogen
Ras homolog enriched in brain
Immunogen Region
endomucin
Isotype
IgG
Molecular Weight
16 kDa
Reactivity
Human
Recommended Dilution
WB: 1:500-1:2000
Synonyms
GTP binding protein Rheb, Ras homolog enriched in brain, RHEB, RHEB2
Uniprot
Q15382
Gene Id
6009
Research Area
Signal Transduction, Neuroscience
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500 - 1:2000; IHC: 1:20 - 1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10350.pdf" target="_blank">Data Sheet</ a>