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Home / Primary Antibodies / Polyclonal Antibodies

Renin receptor,ATP6AP2 antibody

SKU : BHA10807233

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Mfr.No.	FNab07241
Background	ATP6AP2, also named as ATP6IP2, CAPER, ELDF10, N14F, ATP6M8-9, Renin receptor and prorenin receptor, is believed to potentiate the reninangiotensin system(RAS), conferring to prorenin, a likely pathological role at tissue level. The PRR has been identified in the microvascular endothelial cells of the retina, in which it seems to be involved in pathological neovascularization processes. The present study demonstrates for the first time that the PRR is expressed in human ATP6AP2 and suggests a molecular mechanism by which hypertension may exacerbate the pathology of dry AMD.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	ATPase, H+ transporting, lysosomal accessory protein 2
Isotype	IgG
Molecular Weight	47kd
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	APT6M8 9, ATP6AP2, ATP6IP2, ATP6M8 9, CAPER, ELDF10, HT028, M8 9, MRXE, MSTP009, N14F, PRR, PSEC0072, Renin receptor, RENIN RECEPTOR,ATP6AP2, Renin/prorenin receptor, V ATPase M8.9 subunit, XMRE

Uniprot	O75787
Gene Id	10159
Research Area	Signal Transduction, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500-1:1000; IHC: 1:20-1:200

Manual	FNab07241.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807233	FNab07241	100ug	$240		Add to Cart

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