Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II(By similarity).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II (By similarity).
Host
Rabbit
Immunogen
REC8 homolog(yeast)
Isotype
IgG
Molecular Weight
85-95 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
REC8L1
Uniprot
O95072
Gene Id
9985
Research Area
Cell Division and Proliferation, Developmental biology, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)