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Home / Primary Antibodies / Polyclonal Antibodies

PSMC6 antibody

SKU : BHA10806873

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Mfr.No.	FNab06881
Alternative Names	SUG2
Background	The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.
Categories	Primary Antibodies
Clonality	polyclonal
Description	The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.
Host	Rabbit
Immunogen	proteasome (prosome, macropain) 26S subunit, ATPase, 6
Isotype	IgG
Molecular Weight	45 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	SUG2

Uniprot	P62333
Gene Id	5706
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab06881.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806873	FNab06881	100ug	$240		Add to Cart

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