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Home / Primary Antibodies / Polyclonal Antibodies

PPP2CA antibody

SKU : BHA10806704

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Mfr.No.	FNab06712
Background	This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit.
Categories	Primary Antibodies
Clonality	polyclonal
Description	PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.
Host	Rabbit
Immunogen	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
Isotype	IgG
Molecular Weight	36 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO

Uniprot	P67775
Gene Id	5515
Research Area	Cell Division and Proliferation, Cardiovascular, Metabolism, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Reference	Journal: International Journal of Surgery Title: Association between PPP2CA expression and colorectal cancer prognosis Tumour Marker Prognostic Study

Manual	FNab06712.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806704	FNab06712	100ug	$240		Add to Cart

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