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Home / Primary Antibodies / Polyclonal Antibodies

PPAR gamma Antibody - SPC-1308

BHA11917730
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Email
[email protected]
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Swissprot P37231
Accession Number NP_056953.2
Gene Id 5468
Target PPAR gamma
Research Area Diabetes associated, Lipid and lipoprotein Metabolism, Cell Signaling, Epigenetics and Nuclear Signaling, Transcription, Domain Families, Zinc finger, Stem Cells, Mesenchymal Stem Cells, Adipogenesis, Metabolism, Fatty Acids, Redox Metabolism, Fatty Acid Oxidation, Neurodegeneration, ALS Disease, Neuroscience
Buffer PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide
Dilutions WB (1:2000), IHC (1:200); optimal dilutions for assays should be determined by the user.
Purification Peptide Affinity Purified
Purity Highest expression in adipose tissue. Lower in skeletal muscle, spleen, heart and liver. Also detectable in placenta, lung and ovary
Scientific Background Peroxisome proliferators are non genotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family termed peroxisome proliferator activated receptors (PPARs). Nuclear hormone receptors are ligand dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. PPARG is mainly present in adipose tissue, colon and macrophages. Two isoforms of PPARG are detected in the human and in the mouse: PPAR-gamma1 (found in nearly all tissues except muscle) and PPAR-gamma2 (mostly found in adipose tissue and the intestine)
Shipping Temperature Blue Ice or 4°C
Specificity Detects ~56kDa, endogenous levels of total PPAR-gamma
Storage -20ºC
Storage Buffer PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide *Storage buffer may change when conjugated
Storage Temperature -20°C
Applications IHC, WB
Description WB ; IHC
Dilution WB (1:2000), IHC (1:200); optimal dilutions for assays should be determined by the user.
Product Manual SDS
SDS
Reference 1. Chandra, V. et al. (2008) Nature 456 (7220): 350–356.

2. Greene ME et al. (1995) Gene Expr. 4 (4–5): 281–99.

3. Elbrecht A. et al. (1996) Biochem. Biophys. Res. Commun. 224 (2): 431–7.
Combination SKU Supplier No. Conjugate Size Your price Quantity
BHA11917730-1 SPC-1308D Unconjugated 100 ul $286
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BHA11917730-2 SPC-1308D-A390 ATTO 390 100 ul $340
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BHA11917730-3 SPC-1308D-A488 ATTO 488 100 ul $339
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BHA11917730-4 SPC-1308D-A594 ATTO 594 100 ul $339
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BHA11917730-5 SPC-1308D-BI Biotin 100 ul $334
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BHA11917730-6 SPC-1308D-FITC FITC 100 ul $330
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