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Home / Primary Antibodies / Polyclonal Antibodies

PP1A antibody

SKU : BHA10810249

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Mfr.No.	FNab10274
Background	The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Clonality	polyclonal
Host	Rabbit
Immunogen	protein phosphatase 1, catalytic subunit, alpha isoform
Immunogen Region	protein phosphatase 1, catalytic subunit, alpha isoform
Isotype	IgG
Molecular Weight	38kDa
Reactivity	Human, Mouse
Recommended Dilution	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Synonyms	PP-1A, PP1A, PP1alpha, PPP1A, PPP1CA

Uniprot	P62136
Gene Id	5499
Research Area	Epigenetics, Metabolism, Signal Transduction, Neuroscience

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10274.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810249	FNab10274	100ug	$260		Add to Cart

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