Podocalyxin, also known as podocalyxin-like protein 1(PODXL or PCLP1), is a transmembrane glycoprotein belonging to the CD34 family of sialomucins. Podocalyxin was originally identified as the major sialoprotein on podocytes of the kidney glomerulus, but was later found to be expressed on vascular endothelial cells and early hematopoietic progenitors. It Involved in the regulation of both adhesion and cell morphology. In addition, podocalyxin is highly expressed in embryonic stem cells and aberrant expression of podocalyxin has been implicated in a wide range of cancers.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
podocalyxin
Isotype
IgG
Molecular Weight
59 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
GCTM-2 antigen,Gp200,Podocalyxin-like protein 1,PC,PCLP-1,PODXL,PCLP, PCLP1
Uniprot
O00592
Research Area
Stem Cells, Cardiovascular
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)