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Home / Primary Antibodies / Polyclonal Antibodies

PKC gamma antibody

SKU : BHA10806477

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Mfr.No.	FNab06485
Alternative Names	PKCgamma ; PKCC ; PKCG ; PRKCG ; ProteinkinaseCgammatype ; proteinkinaseC ; gamma ; SCA14
Background	Protein kinase C(PKC) is a family of serine-and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC gamma is a neuron-specific member of the classical PKCs and is activated and translocated to subcellular regions as a result of various stimuli, including diacylglycerol synthesis, increased intracellular Ca(2+) and phorbol esters. Defects in this protein have been associated with spinocerebellar ataxia type 14(SCA14), an autosomal dominant neurodegenerative disease.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC gamma is a neuron-specific member of the classical PKCs and is activated and translocated to subcellular regions as a result of various stimuli, including diacylglycerol synthesis, increased intracellular Ca(2+) and phorbol esters. Defects in this protein have been associated with spinocerebellar ataxia type 14 (SCA14), an autosomal dominant neurodegenerative disease.
Host	Rabbit
Immunogen	protein kinase C, gamma
Isotype	IgG
Molecular Weight	78 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	PKC gamma, PKCC, PKCG, PRKCG, Protein kinase C gamma type, protein kinase C, gamma, SCA14

Uniprot	P05129
Gene Id	5582
Research Area	Signal Transduction, Metabolism, Cardiovascular, Immunology, Neuroscience
Weight	78kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, FC, IP

Description

ELISA ; WB ; IHC ; FC ; IP

Dilution

WB	1:500-1:5000
IP	1:200-1:2000
IHC	1:20-1:200
IF	1:50-1:500

Tested Application

WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500

Manual	FNab06485.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806477	FNab06485	100ug	$240		Add to Cart

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